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Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function

Blood vessels are constantly exposed to shear stress, a biomechanical force generated by blood flow. Normal shear stress sensing and barrier function are crucial for vascular homeostasis and are controlled by adherens junctions (AJs). Here we show that AJs are stabilized by the shear stress-induced...

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Detalles Bibliográficos
Autores principales: Stanicek, Laura, Lozano-Vidal, Noelia, Bink, Diewertje Ilse, Hooglugt, Aukie, Yao, Wenjie, Wittig, Ilka, van Rijssel, Jos, van Buul, Jaap Diederik, van Bergen, Anke, Klems, Alina, Ramms, Anne Sophie, Le Noble, Ferdinand, Hofmann, Patrick, Szulcek, Robert, Wang, ShengPeng, Offermanns, Stefan, Ercanoglu, Meryem Seda, Kwon, Hyouk-Bum, Stainier, Didier, Huveneers, Stephan, Kurian, Leo, Dimmeler, Stefanie, Boon, Reinier Abraham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251106/
https://www.ncbi.nlm.nih.gov/pubmed/32457386
http://dx.doi.org/10.1038/s42003-020-0987-0