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Predicting miRNA-based disease-disease relationships through network diffusion on multi-omics biological data

With critical roles in regulating gene expression, miRNAs are strongly implicated in the pathophysiology of many complex diseases. Experimental methods to determine disease related miRNAs are time consuming and costly. Computationally predicting miRNA-disease associations has potential applications...

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Detalles Bibliográficos
Autores principales: Sumathipala, Marissa, Weiss, Scott T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251138/
https://www.ncbi.nlm.nih.gov/pubmed/32457435
http://dx.doi.org/10.1038/s41598-020-65633-6