Activation of Oxytocin Neurons Improves Cardiac Function in a Pressure-Overload Model of Heart Failure

This work shows long-term restoration of the hypothalamic oxytocin (OXT) network preserves OXT release, reduces mortality, cardiac inflammation, fibrosis, and improves autonomic tone and cardiac function in a model of heart failure. Intranasal administration of OXT in patients mimics the short-term...

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Detalles Bibliográficos
Autores principales: Dyavanapalli, Jhansi, Rodriguez, Jeannette, Rocha dos Santos, Carla, Escobar, Joan B., Dwyer, Mary Kate, Schloen, John, Lee, Kyung-min, Wolaver, Whitney, Wang, Xin, Dergacheva, Olga, Michelini, Lisete C., Schunke, Kathryn J., Spurney, Christopher F., Kay, Matthew W., Mendelowitz, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
PRECLINICAL RESEARCH
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251188/
https://www.ncbi.nlm.nih.gov/pubmed/32478209
http://dx.doi.org/10.1016/j.jacbts.2020.03.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251188/
https://www.ncbi.nlm.nih.gov/pubmed/32478209
http://dx.doi.org/10.1016/j.jacbts.2020.03.007

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