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The Innate Immune Response to Herpes Simplex Virus 1 Infection Is Dampened in the Newborn Brain and Can Be Modulated by Exogenous Interferon Beta To Improve Survival

Newborns are particularly susceptible to severe forms of herpes simplex virus 1 (HSV-1) infection, including encephalitis and multisystemic disseminated disease. The underlying age-dependent differences in the immune response that explain this increased susceptibility relative to the adult populatio...

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Detalles Bibliográficos
Autores principales: Giraldo, Daniel, Wilcox, Douglas R., Longnecker, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251210/
https://www.ncbi.nlm.nih.gov/pubmed/32457247
http://dx.doi.org/10.1128/mBio.00921-20