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Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease of unknown etiology. It is characterized by deposition of extracellular matrix proteins, like collagen and fibronectin in the lung interstitium leading to respiratory failure. Our understanding of the pathobiology underlying IPF is st...

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Detalles Bibliográficos
Autores principales: Bueno, Marta, Calyeca, Jazmin, Rojas, Mauricio, Mora, Ana L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251240/
https://www.ncbi.nlm.nih.gov/pubmed/32234292
http://dx.doi.org/10.1016/j.redox.2020.101509