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Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease of unknown etiology. It is characterized by deposition of extracellular matrix proteins, like collagen and fibronectin in the lung interstitium leading to respiratory failure. Our understanding of the pathobiology underlying IPF is st...
Autores principales: | Bueno, Marta, Calyeca, Jazmin, Rojas, Mauricio, Mora, Ana L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251240/ https://www.ncbi.nlm.nih.gov/pubmed/32234292 http://dx.doi.org/10.1016/j.redox.2020.101509 |
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