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Protection against SIV in Rhesus Macaques Using Albumin and CD4-Based Vector-Mediated Gene Transfer

Antibody-like molecules were evaluated with potent simian immunodeficiency virus (SIV) neutralizing properties (immunoadhesins) that were delivered by a recombinant adeno-associated virus (rAAV) vector in the SIV-infected rhesus macaque model. When injected intramuscularly into the host, the vector...

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Detalles Bibliográficos
Autores principales: Spitsin, Sergei, Schnepp, Bruce C., Connell, Mary J., Liu, Tehui, Dang, Christine M., Pappa, Vasiliki, Tustin, Richard, Kinder, Annemarie, Johnson, Philip R., Douglas, Steven D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251311/
https://www.ncbi.nlm.nih.gov/pubmed/32478124
http://dx.doi.org/10.1016/j.omtm.2020.04.019