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Ovariectomy Induces Microglial Cell Activation and Inflammatory Response in Rat Prefrontal Cortices to Accelerate the Chronic Unpredictable Stress-Mediated Anxiety and Depression

Perimenopausal women are associated with increased risks of depression and anxiety, which may be potentially related to the lack of ovarian hormone with antidepression activity in the body. However, the precise mechanism remains unclear so far. This study first adopted the Sprague-Dawley (SD) female...

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Detalles Bibliográficos
Autores principales: Ge, Fei, Yang, Haoran, Lu, Weiting, Shi, Huilian, Chen, Qinlei, Luo, Yi, Liu, Lina, Yan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251427/
https://www.ncbi.nlm.nih.gov/pubmed/32509856
http://dx.doi.org/10.1155/2020/3609758