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Total Aβ(42)/Aβ(40) ratio in plasma predicts amyloid-PET status, independent of clinical AD diagnosis

OBJECTIVE: To explore whether the plasma total β-amyloid (Aβ) Aβ(42)/Aβ(40) ratio is a reliable predictor of the amyloid-PET status by exploring the association between these 2 variables in a subset of the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging cohort. METHODS: Taking pla...

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Detalles Bibliográficos
Autores principales: Doecke, James D., Pérez-Grijalba, Virginia, Fandos, Noelia, Fowler, Christopher, Villemagne, Victor L., Masters, Colin L., Pesini, Pedro, Sarasa, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251518/
https://www.ncbi.nlm.nih.gov/pubmed/32179698
http://dx.doi.org/10.1212/WNL.0000000000009240