Cargando…
Total Aβ(42)/Aβ(40) ratio in plasma predicts amyloid-PET status, independent of clinical AD diagnosis
OBJECTIVE: To explore whether the plasma total β-amyloid (Aβ) Aβ(42)/Aβ(40) ratio is a reliable predictor of the amyloid-PET status by exploring the association between these 2 variables in a subset of the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging cohort. METHODS: Taking pla...
Autores principales: | Doecke, James D., Pérez-Grijalba, Virginia, Fandos, Noelia, Fowler, Christopher, Villemagne, Victor L., Masters, Colin L., Pesini, Pedro, Sarasa, Manuel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251518/ https://www.ncbi.nlm.nih.gov/pubmed/32179698 http://dx.doi.org/10.1212/WNL.0000000000009240 |
Ejemplares similares
-
Plasma amyloid β 42/40 ratios as biomarkers for amyloid β cerebral deposition in cognitively normal individuals
por: Fandos, Noelia, et al.
Publicado: (2017) -
Longitudinal evaluation of the natural history of amyloid-β in plasma and brain
por: Burnham, Samantha C, et al.
Publicado: (2020) -
Validation of Immunoassay-Based Tools for the Comprehensive Quantification of Aβ(40) and Aβ(42) Peptides in Plasma
por: Pérez-Grijalba, Virginia, et al.
Publicado: (2016) -
Plasma Aβ42/40 ratio alone or combined with FDG-PET can accurately predict amyloid-PET positivity: a cross-sectional analysis from the AB255 Study
por: Pérez-Grijalba, Virginia, et al.
Publicado: (2019) -
Outstanding Phenotypic Differences in the Profile of Amyloid-β between Tg2576 and APPswe/PS1dE9 Transgenic Mouse Models of Alzheimer’s Disease
por: Allué, José Antonio, et al.
Publicado: (2016)