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Sindbis Virus with Anti-OX40 Overcomes the Immunosuppressive Tumor Microenvironment of Low-Immunogenic Tumors

Despite remarkable responses to cancer immunotherapy in a subset of patients, many patients remain resistant to therapies. It is now clear that elevated levels of tumor-infiltrating T cells as well as a systemic anti-tumor immune response are requirements for successful immunotherapies. However, the...

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Detalles Bibliográficos
Autores principales: Scherwitzl, Iris, Opp, Silvana, Hurtado, Alicia M., Pampeno, Christine, Loomis, Cynthia, Kannan, Kasthuri, Yu, Minjun, Meruelo, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251545/
https://www.ncbi.nlm.nih.gov/pubmed/32478167
http://dx.doi.org/10.1016/j.omto.2020.04.012