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Spred2 inhibits epithelial-mesenchymal transition of colorectal cancer cells by impairing ERK signaling

Downregulation of the sprouty-related EVH1 domain protein 2 (Spred2) is closely associated with highly metastatic phenotypes in various tumors. However, the roles of Spred2 in the development and progression of colorectal cancer (CRC) are still largely unexplored. As anticipated, Spred2 expression w...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Liu, Shuchen, Kong, Fanxuan, Xiao, Fengjun, Li, Yuxiang, Wang, Hua, Zhang, Shun, Huang, Dandan, Wang, Lisheng, Yang, Yuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251656/
https://www.ncbi.nlm.nih.gov/pubmed/32319644
http://dx.doi.org/10.3892/or.2020.7586