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Extracellular vesicles derived from human ES-MSCs protect retinal ganglion cells and preserve retinal function in a rodent model of optic nerve injury

BACKGROUND: Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive efforts to suppress this neurodegeneration. Various somatic tissue-derived mesenchymal stem cells (MSCs) demonstrated significant neuropr...

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Detalles Bibliográficos
Autores principales: Seyedrazizadeh, Seyedeh-Zahra, Poosti, Sara, Nazari, Abdoreza, Alikhani, Mehdi, Shekari, Faezeh, Pakdel, Farzad, Shahpasand, Koorosh, Satarian, Leila, Baharvand, Hossein
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251703/
https://www.ncbi.nlm.nih.gov/pubmed/32460894
http://dx.doi.org/10.1186/s13287-020-01702-x