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Quantitative proteomic analysis of Rett iPSC-derived neuronal progenitors

BACKGROUND: Rett syndrome (RTT) is a progressive neurodevelopmental disease that is characterized by abnormalities in cognitive, social, and motor skills. RTT is often caused by mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MeCP2). The mechanism by which impaired MeCP2 induce...

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Detalles Bibliográficos
Autores principales: Varderidou-Minasian, Suzy, Hinz, Lisa, Hagemans, Dominique, Posthuma, Danielle, Altelaar, Maarten, Heine, Vivi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251722/
https://www.ncbi.nlm.nih.gov/pubmed/32460858
http://dx.doi.org/10.1186/s13229-020-00344-3