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Microbial Stimulation Reverses the Age-Related Decline in M Cells in Aged Mice

Aging has a profound effect on the immune system, termed immunosenescence, resulting in increased incidence and severity of infections and decreased efficacy of vaccinations. We previously showed that immunosurveillance in the intestine, achieved primarily through antigen sampling M cells in the fol...

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Detalles Bibliográficos
Autores principales: Donaldson, David S., Pollock, Jolinda, Vohra, Prerna, Stevens, Mark P., Mabbott, Neil A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251786/
https://www.ncbi.nlm.nih.gov/pubmed/32454449
http://dx.doi.org/10.1016/j.isci.2020.101147