Leptin facilitates the differentiation of Th17 cells from MRL/Mp-Fas lpr lupus mice by activating NLRP3 inflammasome

Both NLRP3 inflammasome and Th17 cells play important roles in the pathogenesis of systemic lupus erythematosus (SLE). Here we tried to investigate whether leptin promotes the differentiation of Th17 cells from lupus mice by activating the NLRP3 inflammasome. Th17 cells induced from MRL/Mp-Fas lpr m...

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Detalles Bibliográficos
Autores principales: Yu, Yiyun, Fu, Sisi, Zhang, Xianglin, Wang, Lingbiao, Zhao, Li, Wan, Weiguo, Xue, Yu, Lv, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251789/
https://www.ncbi.nlm.nih.gov/pubmed/31752571
http://dx.doi.org/10.1177/1753425919886643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251789/
https://www.ncbi.nlm.nih.gov/pubmed/31752571
http://dx.doi.org/10.1177/1753425919886643

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