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Dysregulation of protein synthesis and dendritic spine morphogenesis in ASD: studies in human pluripotent stem cells

Autism spectrum disorder (ASD) is a brain disorder that involves changes in neuronal connections. Abnormal morphology of dendritic spines on postsynaptic neurons has been observed in ASD patients and transgenic mice that model different monogenetic causes of ASD. A number of ASD-associated genetic v...

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Detalles Bibliográficos
Autores principales: Lo, Louisa Hoi-Ying, Lai, Kwok-On
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251853/
https://www.ncbi.nlm.nih.gov/pubmed/32460854
http://dx.doi.org/10.1186/s13229-020-00349-y