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Construction of reporter gene assays using CWP and PDR mutant yeasts for enhanced detection of various sex steroids
BACKGROUND: Sex steroid hormone receptors are classified into three classes of receptors: estrogen receptors (ER) α and β, androgen receptor (AR), and progesterone receptor (PR). They belong to the nuclear receptor superfamily and activate their downstream genes in a ligand-dependent manner. Since s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251871/ https://www.ncbi.nlm.nih.gov/pubmed/32514322 http://dx.doi.org/10.1186/s41021-020-00159-x |