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Single-cell RNA sequencing reveals the tumor microenvironment and facilitates strategic choices to circumvent treatment failure in a chemorefractory bladder cancer patient

BACKGROUND: Tumor cell-intrinsic mechanisms and complex interactions with the tumor microenvironment contribute to therapeutic failure via tumor evolution. It may be possible to overcome treatment resistance by developing a personalized approach against relapsing cancers based on a comprehensive ana...

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Detalles Bibliográficos
Autores principales: Lee, Hye Won, Chung, Woosung, Lee, Hae-Ock, Jeong, Da Eun, Jo, Areum, Lim, Joung Eun, Hong, Jeong Hee, Nam, Do-Hyun, Jeong, Byong Chang, Park, Se Hoon, Joo, Kyeung-Min, Park, Woong-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251908/
https://www.ncbi.nlm.nih.gov/pubmed/32460812
http://dx.doi.org/10.1186/s13073-020-00741-6