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Random Parametric Perturbations of Gene Regulatory Circuit Uncover State Transitions in Cell Cycle

Many biological processes involve precise cellular state transitions controlled by complex gene regulation. Here, we use budding yeast cell cycle as a model system and explore how a gene regulatory circuit encodes essential information of state transitions. We present a generalized random circuit pe...

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Detalles Bibliográficos
Autores principales: Katebi, Ataur, Kohar, Vivek, Lu, Mingyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251928/
https://www.ncbi.nlm.nih.gov/pubmed/32450514
http://dx.doi.org/10.1016/j.isci.2020.101150