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Random Parametric Perturbations of Gene Regulatory Circuit Uncover State Transitions in Cell Cycle
Many biological processes involve precise cellular state transitions controlled by complex gene regulation. Here, we use budding yeast cell cycle as a model system and explore how a gene regulatory circuit encodes essential information of state transitions. We present a generalized random circuit pe...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251928/ https://www.ncbi.nlm.nih.gov/pubmed/32450514 http://dx.doi.org/10.1016/j.isci.2020.101150 |