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CDYL2 Epigenetically Regulates MIR124 to Control NF-κB/STAT3-Dependent Breast Cancer Cell Plasticity

Epigenetic deregulation of gene transcription is central to cancer cell plasticity and malignant progression but remains poorly understood. We found that the uncharacterized epigenetic factor chromodomain on Y-like 2 (CDYL2) is commonly over-expressed in breast cancer, and that high CDYL2 levels cor...

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Detalles Bibliográficos
Autores principales: Siouda, Maha, Dujardin, Audrey D., Barbollat-Boutrand, Laetitia, Mendoza-Parra, Marco A., Gibert, Benjamin, Ouzounova, Maria, Bouaoud, Jebrane, Tonon, Laurie, Robert, Marie, Foy, Jean-Philippe, Lavergne, Vincent, Manie, Serge N., Viari, Alain, Puisieux, Alain, Ichim, Gabriel, Gronemeyer, Hinrich, Saintigny, Pierre, Mulligan, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251929/
https://www.ncbi.nlm.nih.gov/pubmed/32450513
http://dx.doi.org/10.1016/j.isci.2020.101141