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CDYL2 Epigenetically Regulates MIR124 to Control NF-κB/STAT3-Dependent Breast Cancer Cell Plasticity
Epigenetic deregulation of gene transcription is central to cancer cell plasticity and malignant progression but remains poorly understood. We found that the uncharacterized epigenetic factor chromodomain on Y-like 2 (CDYL2) is commonly over-expressed in breast cancer, and that high CDYL2 levels cor...
Autores principales: | Siouda, Maha, Dujardin, Audrey D., Barbollat-Boutrand, Laetitia, Mendoza-Parra, Marco A., Gibert, Benjamin, Ouzounova, Maria, Bouaoud, Jebrane, Tonon, Laurie, Robert, Marie, Foy, Jean-Philippe, Lavergne, Vincent, Manie, Serge N., Viari, Alain, Puisieux, Alain, Ichim, Gabriel, Gronemeyer, Hinrich, Saintigny, Pierre, Mulligan, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251929/ https://www.ncbi.nlm.nih.gov/pubmed/32450513 http://dx.doi.org/10.1016/j.isci.2020.101141 |
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