Integration of Comprehensive Genomic Analysis and Functional Screening of Affected Molecular Pathways to Inform Cancer Therapy

OBJECTIVE: To select optimal therapies based on the detection of actionable genomic alterations in tumor samples is a major challenge in precision medicine. METHODS: We describe an effective process (opened December 1, 2017) that combines comprehensive genomic and transcriptomic tumor profiling, cus...

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Detalles Bibliográficos
Autores principales: Vasmatzis, George, Liu, Minetta C., Reganti, Sowjanya, Feathers, Ryan W., Smadbeck, James, Johnson, Sarah H., Schaefer Klein, Janet L., Harris, Faye R., Yang, Lin, Kosari, Farhad, Murphy, Stephen J., Borad, Mitesh J., Thompson, E. Aubrey, Cheville, John C., Anastasiadis, Panos Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251931/
https://www.ncbi.nlm.nih.gov/pubmed/31685261
http://dx.doi.org/10.1016/j.mayocp.2019.07.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251931/
https://www.ncbi.nlm.nih.gov/pubmed/31685261
http://dx.doi.org/10.1016/j.mayocp.2019.07.019

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