Optic Atrophy 1 Controls Human Neuronal Development by Preventing Aberrant Nuclear DNA Methylation

Optic atrophy 1 (OPA1), a GTPase at the inner mitochondrial membrane involved in regulating mitochondrial fusion, stability, and energy output, is known to be crucial for neural development: Opa1 heterozygous mice show abnormal brain development, and inactivating mutations in OPA1 are linked to huma...

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Detalles Bibliográficos
Autores principales: Caglayan, Safak, Hashim, Adnan, Cieslar-Pobuda, Artur, Jensen, Vidar, Behringer, Sidney, Talug, Burcu, Chu, Dinh Toi, Pecquet, Christian, Rogne, Marie, Brech, Andreas, Brorson, Sverre Henning, Nagelhus, Erlend Arnulf, Hannibal, Luciana, Boschi, Antonella, Taskén, Kjetil, Staerk, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251951/
https://www.ncbi.nlm.nih.gov/pubmed/32450518
http://dx.doi.org/10.1016/j.isci.2020.101154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251951/
https://www.ncbi.nlm.nih.gov/pubmed/32450518
http://dx.doi.org/10.1016/j.isci.2020.101154

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