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Dexmedetomidine Attenuates Glutamate-Induced Cytotoxicity by Inhibiting the Mitochondrial-Mediated Apoptotic Pathway

BACKGROUND: Glutamate (GLU) is the most excitatory amino acid in the central nervous system and plays an important role in maintaining the normal function of the nervous system. During cerebral ischemia, massive release of GLU leads to neuronal necrosis and apoptosis. It has been reported that dexme...

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Detalles Bibliográficos
Autores principales: Zhang, Weidong, Yu, Jun, Guo, Mengzhuo, Ren, Bo, Tian, Yanyan, Hu, Qinggang, Xie, Qun, Xu, Chen, Feng, Zeguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251967/
https://www.ncbi.nlm.nih.gov/pubmed/32419697
http://dx.doi.org/10.12659/MSM.922139