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Cardioprotective effects of pharmacological blockade of the mitochondrial calcium uniporter on myocardial ischemia-reperfusion injury
PURPOSE: To evaluate whether the attenuation of mitochondrial Ca(2+) overload produced by pharmacological blockade of mitochondrial Ca(2+) uniporter (MCU) protects the myocardium against injuries caused by cardiac ischemia and reperfusion (CIR). METHODS: CIR was induced in adult male Wistar rats (30...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7251977/ https://www.ncbi.nlm.nih.gov/pubmed/32692797 http://dx.doi.org/10.1590/s0102-865020200030000006 |