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Dopamine D3 receptor-based medication development for the treatment of opioid use disorder: Rationale, progress, and challenges

Opioid abuse and related overdose deaths continue to rise in the United States, contributing to the current national opioid crisis. Although several opioid-based pharmacotherapies are available (e.g., methadone, buprenorphine, naloxone), they show limited effectiveness in long-term relapse preventio...

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Detalles Bibliográficos
Autores principales: Galaj, Ewa, Newman, Amy Hauck, Xi, Zheng-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252042/
https://www.ncbi.nlm.nih.gov/pubmed/32376243
http://dx.doi.org/10.1016/j.neubiorev.2020.04.024