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Dopamine D3 receptor-based medication development for the treatment of opioid use disorder: Rationale, progress, and challenges
Opioid abuse and related overdose deaths continue to rise in the United States, contributing to the current national opioid crisis. Although several opioid-based pharmacotherapies are available (e.g., methadone, buprenorphine, naloxone), they show limited effectiveness in long-term relapse preventio...
Autores principales: | Galaj, Ewa, Newman, Amy Hauck, Xi, Zheng-Xiong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Ltd.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252042/ https://www.ncbi.nlm.nih.gov/pubmed/32376243 http://dx.doi.org/10.1016/j.neubiorev.2020.04.024 |
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