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Interleukin-1 blockade with high-dose anakinra in patients with COVID-19, acute respiratory distress syndrome, and hyperinflammation: a retrospective cohort study

BACKGROUND: Mortality of patients with coronavirus disease 2019 (COVID-19), acute respiratory distress syndrome (ARDS), and systemic inflammation is high. In areas of pandemic outbreak, the number of patients can exceed maximum capacity of intensive care units (ICUs), and, thus, these individuals of...

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Detalles Bibliográficos
Autores principales: Cavalli, Giulio, De Luca, Giacomo, Campochiaro, Corrado, Della-Torre, Emanuel, Ripa, Marco, Canetti, Diana, Oltolini, Chiara, Castiglioni, Barbara, Tassan Din, Chiara, Boffini, Nicola, Tomelleri, Alessandro, Farina, Nicola, Ruggeri, Annalisa, Rovere-Querini, Patrizia, Di Lucca, Giuseppe, Martinenghi, Sabina, Scotti, Raffaella, Tresoldi, Moreno, Ciceri, Fabio, Landoni, Giovanni, Zangrillo, Alberto, Scarpellini, Paolo, Dagna, Lorenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252085/
https://www.ncbi.nlm.nih.gov/pubmed/32501454
http://dx.doi.org/10.1016/S2665-9913(20)30127-2