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Tropism, replication competence, and innate immune responses of the coronavirus SARS-CoV-2 in human respiratory tract and conjunctiva: an analysis in ex-vivo and in-vitro cultures

BACKGROUND: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in December 2019, causing a respiratory disease (coronavirus disease 2019, COVID-19) of varying severity in Wuhan, China, and subsequently leading to a pandemic. The transmissibility and pathogenesis of SARS-CoV-2 remai...

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Detalles Bibliográficos
Autores principales: Hui, Kenrie P Y, Cheung, Man-Chun, Perera, Ranawaka A P M, Ng, Ka-Chun, Bui, Christine H T, Ho, John C W, Ng, Mandy M T, Kuok, Denise I T, Shih, Kendrick C, Tsao, Sai-Wah, Poon, Leo L M, Peiris, Malik, Nicholls, John M, Chan, Michael C W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252187/
https://www.ncbi.nlm.nih.gov/pubmed/32386571
http://dx.doi.org/10.1016/S2213-2600(20)30193-4