The Senolytic Drug Navitoclax (ABT-263) Causes Trabecular Bone Loss and Impaired Osteoprogenitor Function in Aged Mice

Senescence is a cellular defense mechanism that helps cells prevent acquired damage, but chronic senescence, as in aging, can contribute to the development of age-related tissue dysfunction and disease. Previous studies clearly show that removal of senescent cells can help prevent tissue dysfunction...

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Detalles Bibliográficos
Autores principales: Sharma, Anuj K., Roberts, Rachel L., Benson, Reginald D., Pierce, Jessica L., Yu, Kanglun, Hamrick, Mark W., McGee-Lawrence, Meghan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252306/
https://www.ncbi.nlm.nih.gov/pubmed/32509782
http://dx.doi.org/10.3389/fcell.2020.00354

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252306/
https://www.ncbi.nlm.nih.gov/pubmed/32509782
http://dx.doi.org/10.3389/fcell.2020.00354

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