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Metformin Ameliorates Diabetic Cardiomyopathy by Activating the PK2/PKR Pathway
Diabetic cardiomyopathy (DCM) is a complication of diabetes that can cause damage to myocardial structure and function. Metformin (Met) is a widely used type 2 diabetes treatment drug that exerts cardioprotective effects through multiple pathways. Prokineticin 2 (PK2) is a small-molecule secreted pr...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252307/ https://www.ncbi.nlm.nih.gov/pubmed/32508669 http://dx.doi.org/10.3389/fphys.2020.00425 |