Doxorubicin selectively induces apoptosis through the inhibition of a novel isoform of Bcl-2 in acute myeloid leukaemia MOLM-13 cells with reduced Beclin 1 expression

The overexpression of anti-apoptotic Bcl-2 in acute myeloid leukaemia (AML) may contribute to difficulties in eradicating these cells during chemotherapy. In the present study, doxorubicin (Dox) was evaluated for its potential to induce selective apoptotic cell death in AML MOLM-13 cells and to modu...

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Detalles Bibliográficos
Autores principales: Vu, Milan, Kassouf, Nick, Ofili, Rosemary, Lund, Torben, Bell, Celia, Appiah, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252449/
https://www.ncbi.nlm.nih.gov/pubmed/32377726
http://dx.doi.org/10.3892/ijo.2020.5052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252449/
https://www.ncbi.nlm.nih.gov/pubmed/32377726
http://dx.doi.org/10.3892/ijo.2020.5052

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