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HSulf-1 and palbociclib exert synergistic antitumor effects on RB-positive triple-negative breast cancer

Human sulfatase-1 (HSulf-1) is emerging as a novel prognostic biomarker in breast cancer. Previous studies demonstrated HSulf-1 to function as a negative regulator of cyclin D1 in breast cancer. Accumulating preclinical evidence is supporting the efficacy of cyclin-dependent kinase (CDK) 4/6 inhibit...

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Detalles Bibliográficos
Autores principales: Chen, Fengxia, Zhang, Zhicai, Yu, Yihan, Liu, Qiuyu, Pu, Feifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252455/
https://www.ncbi.nlm.nih.gov/pubmed/32377705
http://dx.doi.org/10.3892/ijo.2020.5057