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Identification of the cis-molecular neighbours of the immune checkpoint protein B7-H4 in the breast cancer cell-line SK-BR-3 by proteomic proximity labelling

The immune checkpoint protein B7-H4 plays an important role in the positive as well as the negative regulation of immune T-cell responses. When expressed on cancer cells, B7-H4 inhibits T-cell activity, and numerous types of cancer cells use upregulation of B7-H4 as a survival strategy. Thus, B7-H4...

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Detalles Bibliográficos
Autores principales: Rees, Johanna S., Cheung, Lawrence C.C., Hamaia, Samir W., Davies, Gareth, Sandercock, Alan, Lilley, Kathryn S., Tigue, Natalie, Jackson, Antony P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252456/
https://www.ncbi.nlm.nih.gov/pubmed/32319587
http://dx.doi.org/10.3892/ijo.2020.5037