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High expression of immune checkpoints is associated with the TIL load, mutation rate and patient survival in colorectal cancer

Adoptive cell therapy with the use of tumor-infiltrating lymphocytes (TILs) is a very promising immunotherapeutic approach for the treatment of patients with colorectal cancer (CRC). However, within the tumor microenvironment, co-inhibitory immune checkpoints can inactivate TILs. The aim of the pres...

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Detalles Bibliográficos
Autores principales: Kitsou, Mara, Ayiomamitis, Georgios D., Zaravinos, Apostolos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252459/
https://www.ncbi.nlm.nih.gov/pubmed/32468013
http://dx.doi.org/10.3892/ijo.2020.5062