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High expression of immune checkpoints is associated with the TIL load, mutation rate and patient survival in colorectal cancer
Adoptive cell therapy with the use of tumor-infiltrating lymphocytes (TILs) is a very promising immunotherapeutic approach for the treatment of patients with colorectal cancer (CRC). However, within the tumor microenvironment, co-inhibitory immune checkpoints can inactivate TILs. The aim of the pres...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
D.A. Spandidos
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252459/ https://www.ncbi.nlm.nih.gov/pubmed/32468013 http://dx.doi.org/10.3892/ijo.2020.5062 |