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USP7 deubiquitinates and stabilizes EZH2 in prostate cancer cells

Regulation of target proteins by the ubiquitin-proteasome system (UPS) is common in a wide range of cellular events, including transcriptional regulation, cell cycle progression, differentiation, and tumorigenesis. Ubiquitin-specific protease 7 (USP7) has been implicated in tumor development and met...

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Detalles Bibliográficos
Autores principales: Lee, Jae Eun, Park, Chan Mi, Kim, Jung Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Genética 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252518/
https://www.ncbi.nlm.nih.gov/pubmed/32453339
http://dx.doi.org/10.1590/1678-4685-GMB-2019-0338