Structure-based drug repositioning explains ibrutinib as VEGFR2 inhibitor

Many drugs are promiscuous and bind to multiple targets. On the one hand, these targets may be linked to unwanted side effects, but on the other, they may achieve a combined desired effect (polypharmacology) or represent multiple diseases (drug repositioning). With the growth of 3D structures of dru...

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Detalles Bibliográficos
Autores principales: Adasme, Melissa F., Parisi, Daniele, Van Belle, Kristien, Salentin, Sebastian, Haupt, V. Joachim, Jennings, Gary S., Heinrich, Jörg-Christian, Herman, Jean, Sprangers, Ben, Louat, Thierry, Moreau, Yves, Schroeder, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252619/
https://www.ncbi.nlm.nih.gov/pubmed/32459810
http://dx.doi.org/10.1371/journal.pone.0233089

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252619/
https://www.ncbi.nlm.nih.gov/pubmed/32459810
http://dx.doi.org/10.1371/journal.pone.0233089

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