Cargando…
Structure-based drug repositioning explains ibrutinib as VEGFR2 inhibitor
Many drugs are promiscuous and bind to multiple targets. On the one hand, these targets may be linked to unwanted side effects, but on the other, they may achieve a combined desired effect (polypharmacology) or represent multiple diseases (drug repositioning). With the growth of 3D structures of dru...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252619/ https://www.ncbi.nlm.nih.gov/pubmed/32459810 http://dx.doi.org/10.1371/journal.pone.0233089 |