Depletion of Ric-8B leads to reduced mTORC2 activity

mTOR, a serine/threonine protein kinase that is involved in a series of critical cellular processes, can be found in two functionally distinct complexes, mTORC1 and mTORC2. In contrast to mTORC1, little is known about the mechanisms that regulate mTORC2. Here we show that mTORC2 activity is reduced...

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Detalles Bibliográficos
Autores principales: Nagai, Maíra H., Xavier, Victor P. S., Gutiyama, Luciana M., Machado, Cleiton F., Reis, Alice H., Donnard, Elisa R., Galante, Pedro A. F., Abreu, Jose G., Festuccia, William T., Malnic, Bettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252638/
https://www.ncbi.nlm.nih.gov/pubmed/32392211
http://dx.doi.org/10.1371/journal.pgen.1008255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252638/
https://www.ncbi.nlm.nih.gov/pubmed/32392211
http://dx.doi.org/10.1371/journal.pgen.1008255

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