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Temozolomide antagonizes oncolytic immunovirotherapy in glioblastoma

BACKGROUND: Temozolomide (TMZ) chemotherapy is a current standard of care for glioblastoma (GBM), however it has only extended overall survival by a few months. Because it also modulates the immune system, both beneficially and negatively, understanding how TMZ interacts with immunotherapeutics is i...

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Detalles Bibliográficos
Autores principales:	Saha, Dipongkor, Rabkin, Samuel D, Martuza, Robert L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2020
Materias:	Oncolytic and Local Immunotherapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7252967/ https://www.ncbi.nlm.nih.gov/pubmed/32457126 http://dx.doi.org/10.1136/jitc-2019-000345

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