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Obesity and STING1 genotype associate with 23-valent pneumococcal vaccination efficacy

BACKGROUND: Obesity has been associated with attenuated vaccine responses and an increased risk of contracting pneumococcal pneumonia, but no study to our knowledge has assessed the impact of obesity and genetics on 23-valent pneumococcal vaccine (PPSV23) efficacy. We assessed the relationship of ob...

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Detalles Bibliográficos
Autores principales: Sebastian, Mathew, Hsiao, Chu J., Futch, Hunter S., Eisinger, Robert S., Dumeny, Leanne, Patel, Seema, Gobena, Mesfin, Katikaneni, Divya S., Cohen, Joel, Carpenter, Anne-Marie, Spiryda, Lisa, Heldermon, Coy D., Jin, Lei, Brantly, Mark L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253011/
https://www.ncbi.nlm.nih.gov/pubmed/32376795
http://dx.doi.org/10.1172/jci.insight.136141