A human induced pluripotent stem cell‐derived cortical neuron human‐on‐a chip system to study Aβ(42) and tau‐induced pathophysiological effects on long‐term potentiation

INTRODUCTION: The quest to identify an effective therapeutic strategy for neurodegenerative diseases, such as mild congitive impairment (MCI) and Alzheimer's disease (AD), suffers from the lack of good human‐based models. Animals represent the most common models used in basic research and drug...

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Detalles Bibliográficos
Autores principales: Caneus, Julbert, Akanda, Nesar, Rumsey, John W., Guo, Xiufang, Jackson, Max, Long, Christopher J., Sommerhage, Frank, Georgieva, Sanya, Kanaan, Nicholas M., Morgan, David, Hickman, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253154/
https://www.ncbi.nlm.nih.gov/pubmed/32490141
http://dx.doi.org/10.1002/trc2.12029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253154/
https://www.ncbi.nlm.nih.gov/pubmed/32490141
http://dx.doi.org/10.1002/trc2.12029

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