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A caveolin binding motif in Na/K-ATPase is required for stem cell differentiation and organogenesis in mammals and C. elegans

Several signaling events have been recognized as essential for regulating cell lineage specification and organogenesis in animals. We find that the gain of an amino-terminal caveolin binding motif (CBM) in the α subunit of the Na/K–adenosine triphosphatase (ATPase) (NKA) is required for the early st...

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Detalles Bibliográficos
Autores principales: Wang, Xiaoliang, Cai, Liquan, Xie, Jeffrey X., Cui, Xiaoyu, Zhang, Jue, Wang, Jiayan, Chen, Yiliang, Larre, Isabel, Shapiro, Joseph I., Pierre, Sandrine V., Wu, Dianqing, Zhu, Guo-Zhang, Xie, Zijian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253156/
https://www.ncbi.nlm.nih.gov/pubmed/32537485
http://dx.doi.org/10.1126/sciadv.aaw5851