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Activated α(IIb)β(3) on platelets mediates flow-dependent NETosis via SLC44A2
Platelet-neutrophil interactions are important for innate immunity, but also contribute to the pathogenesis of deep vein thrombosis, myocardial infarction and stroke. Here we report that, under flow, von Willebrand factor/glycoprotein Ibα-dependent platelet ‘priming’ induces integrin α(IIb)β(3) acti...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253179/ https://www.ncbi.nlm.nih.gov/pubmed/32314961 http://dx.doi.org/10.7554/eLife.53353 |