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Activated α(IIb)β(3) on platelets mediates flow-dependent NETosis via SLC44A2

Platelet-neutrophil interactions are important for innate immunity, but also contribute to the pathogenesis of deep vein thrombosis, myocardial infarction and stroke. Here we report that, under flow, von Willebrand factor/glycoprotein Ibα-dependent platelet ‘priming’ induces integrin α(IIb)β(3) acti...

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Detalles Bibliográficos
Autores principales:	Constantinescu-Bercu, Adela, Grassi, Luigi, Frontini, Mattia, Salles-Crawley, Isabelle I, Woollard, Kevin, Crawley, James TB
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2020
Materias:	Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253179/ https://www.ncbi.nlm.nih.gov/pubmed/32314961 http://dx.doi.org/10.7554/eLife.53353

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