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IP(3) mediated global Ca(2+) signals arise through two temporally and spatially distinct modes of Ca(2+) release
The ‘building-block’ model of inositol trisphosphate (IP(3))-mediated Ca(2+) liberation posits that cell-wide cytosolic Ca(2+) signals arise through coordinated activation of localized Ca(2+) puffs generated by stationary clusters of IP(3) receptors (IP(3)Rs). Here, we revise this hypothesis, applyi...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253181/ https://www.ncbi.nlm.nih.gov/pubmed/32396066 http://dx.doi.org/10.7554/eLife.55008 |