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Estrogen Receptor-α Quantification in Breast Cancer: Concordance Between Immunohistochemical Assays and mRNA-In Situ Hybridization for ESR1 Gene

Immunohistochemical (IHC) quantification of estrogen receptor-α (ER) is used for assessment of treatment regimen in breast cancer. Different ER IHC assays may produce diverging results, because of different antibody clones, protocols, and stainer platforms. Objective tissue-based techniques to asses...

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Detalles Bibliográficos
Autores principales: Thomsen, Christian, Nielsen, Søren, Nielsen, Boye S., Pedersen, Sine H., Vyberg, Mogens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253185/
https://www.ncbi.nlm.nih.gov/pubmed/30920963
http://dx.doi.org/10.1097/PAI.0000000000000760