Population Bottlenecks Strongly Influence the Evolutionary Trajectory to Fluoroquinolone Resistance in Escherichia coli

Experimental evolution is a powerful tool to study genetic trajectories to antibiotic resistance under selection. A confounding factor is that outcomes may be heavily influenced by the choice of experimental parameters. For practical purposes (minimizing culture volumes), most experimental evolution...

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Detalles Bibliográficos
Autores principales: Garoff, Linnéa, Pietsch, Franziska, Huseby, Douglas L, Lilja, Tua, Brandis, Gerrit, Hughes, Diarmaid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253196/
https://www.ncbi.nlm.nih.gov/pubmed/32031639
http://dx.doi.org/10.1093/molbev/msaa032

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7253196/
https://www.ncbi.nlm.nih.gov/pubmed/32031639
http://dx.doi.org/10.1093/molbev/msaa032

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